Anadrol is known as one of the strongest oral anabolic steroids on the market. It constantly competes with Dianabol (Methandrostenolone), and there is an ongoing debate in the steroid-using bodybuilding community over which drug is stronger.
Аnabolic steroid better known as oxymetholone
Anadrol is the brand name and trade name of an anabolic steroid better known as oxymetholone. But not to be confused with Oxandrolone which is also called Anavar. Oxymetholone is Anadrol. The Anadrol formula was first developed and introduced in 1959. Almost immediately, Syntex began marketing Oxymetholone under the brand name Anadrol-50. At the same time, Parke Davis & Co also manufactured the drug, but marketed it under the name Anadroyd. Shortly after entering the pharmaceutical market, Anadrol was used to treat a variety of ailments ranging from geriatric atrophy to fighting infections. However, Anadrol gained notoriety and popularity precisely as a medication used to treat anemia. Anemia patients are prescribed Anadrol to increase the number of red blood cells and increase the level of hemoglobin in the blood. With the development of drugs, less dangerous drugs began to be used in therapy, and the release of Anapolon was significantly reduced.
Anadrol has the ability to rapidly stimulate erythropoiesis (hematopoiesis). Despite the fact that all anabolic steroids are endowed with similar properties, Anadrol shows better hematopoiesis than other drugs. For a more accurate characterization, it should be noted that Anadrol increases the production of red blood cells by 5 times. Studies have shown that Anadrol has a marked anabolic effect in muscular dystrophy patients diagnosed with AIDS. Patients taking Anadrol gained up to 8 kg, while the placebo groups not only lost weight but also had increased mortality. Thanks to the discovery of new properties of the drug, production was resumed and Anadrol became a priority for patients with malnutrition caused by the immunodeficiency virus.
Anabolic steroid dihydrotestosterone
Anadrol is a derivative of the anabolic steroid dihydrotestosterone (DHT). In fact, Anadrol is a modified dihydrotestosterone. Compounds belonging to the DHT family of anabolic steroids include: Winstrol, Primobolan, Masteron, Anavar, as well as a number of other drugs derived from the anabolic steroid DHT. All these analogues are united by the fact that they belong to the group of modified forms of DHT. Dihydrotestosterone can be considered the “father” or “grandmother” hormone of these anabolic steroids. What differentiates Anadrol from the original DHT hormone is the extra methyl group and the 2-hydroxymethylene group attached to the carbon of the first cycloalkane ring of the steroid’s backbone. Under the influence of the enzyme 3-hydroxysteroid dehydrogenase (present in large quantities in the muscles), dihydrotestosterone, penetrating the muscle tissue, becomes inactive and reduced to other metabolites. Due to its structure, Anadrol does not interact with the enzyme 3-hydroxysteroid dehydrogenase and remains active in muscle tissue. This gives Anadrol very high potential: it has an anabolic index of 320, which is just over 3 times higher than testosterone, which has a rating of 100. Anadrol also has low androgenic activity. Compared to testosterone, which has an androgenic index of 100, Anadrol’s androgenic index is 45.
One of the unique and unexplored features of Anadrol is that, as a derivative of dihydrotestosterone, it has very high estrogenic activity. Normally, anabolic steroids that are derived from DHT do not have the ability to convert to estrogen through the aromatase enzyme and therefore have no estrogenic effect. In this respect, Anapolon is clearly different from the rest. Anadrol is known to cause water retention, gynecomastia, and other estrogen-like side effects without even converting to estrogen. Anadrol is believed to act like estrogen in certain tissues. This feature is described and discussed in detail below. But those who follow Anadrol closely should understand that the drug is a DHT derivative but does not exhibit the inherent effects and effectiveness of dihydrotestosterone. Anadrol cannot convert to estrogen, as aromatase inhibitors do not treat the typical estrogenic symptoms of the drug.
Anadrol is an oral anabolic steroid. This means that the substance has to pass through the liver before it enters the bloodstream.night The C17 alpha alkyd group, which preserves the integrity and permeability of the drug, helps Anadrol not to be destroyed under the influence of metabolic processes. Severe hepatotoxicity is a well-known feature of Anadrol. The chemical structure and modification of the drug (including the presence of a C17 alpha alkyd group) make it extremelyresistant to liver disease. Metabolism. Simply put, Anadrol is not broken down as it passes through the liver. However, the more the substance reacts to biochemical processes, the greater the stress it places on the body. This is indicative of the extreme toxicity of Anadrol, known to be one of the most harmful oral anabolic steroids available.